From Baltimore: From the Baltimore (Maryland) Beltway, I695, take I97 south to Rt. 50/301 east to the Chesapeake Bay Bridge. Once on the Eastern Shore, stay on Rt. 50 to Cambridge, MD, crossing the Choptank River on the Frederick Malkus Bridge.
From Washington D.C.: Take Rt 50 east from the Washington DC Beltway I95/495, to Cambridge, MD on Maryland's Eastern Shore, crossing the Choptank River on the Frederick Malkus Bridge. After the bridge, go to 3rd stop light and turn right. Go one block and turn right again onto Washington St. (Rt. 343). Stay on this road for about 3.5 miles.  Look for the UMCES sign on the right side of the road.  Bear right on Horn Point Rd. Continue for about 1.5 miles. The entrance to the lab is flanked by two statues of sheep. The reception desk is in the first building on the right at about .5 miles down the lane. Map of Horn Point Campus